Recombinant Human Beta Klotho Protein, His Tag-细胞/细菌培养-试剂-生物在线
翌圣生物科技(上海)股份有限公司
Recombinant Human Beta Klotho Protein, His Tag

Recombinant Human Beta Klotho Protein, His Tag

商家询价

产品名称: Recombinant Human Beta Klotho Protein, His Tag

英文名称: Recombinant Human Beta Klotho Protein, His Tag

产品编号: 94201ES25

产品价格: 0

产品产地: Yeasen

品牌商标: Yeasen

更新时间: 2024-12-10T13:22:33

使用范围: null

翌圣生物科技(上海)股份有限公司
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产品描述

 

Beta-klotho (KLB) is a coreceptor required for endocrine fibroblast growth factor (FGF) 15/19 and FGF21 signaling in the brain.  Like Klotho, Klotho beta facilitates binding between FGF19 subfamily members and their receptors via formation of a ternary complex. The Klotho beta mediated interaction of human FGF19 with FGF Receptor 4 in the liver negatively regulates bile acid synthesis by controlling the secretion of two key bile acid synthase genes, cholesterol 7-alpha hydroxylase and sterol 12-alpha hydroxylase

 

产品性质

 

Synonyms

betaKlotho; beta-klotho; BKL; KLB; klotho beta like; Klotho beta; β-klotho; klotho β like; Klotho β

Uniprot No.

Q86Z14

Source

HEK293 Cells-derived Human Beta Klotho ProteinMet30-Thr983 with His tag at the C-terminal

Molecular Weight

Approximately 111.6 kDa. Due to glycosylation, the protein migrates to 115-130 kDa based on Tris-Bis PAGE result.

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Purity

95as determined by SDS-PAGE and HPLC

Endotoxin

1.0 EU per 1μg of the protein by the LAL method.

Formulation

TUNEology 波长可调检测卡盒-->