FITC标记的同源盒蛋白D4抗体
产品名称： FITC标记的同源盒蛋白D4抗体
英文名称： Anti-HOXD4/FITC
产品编号： HZ-17372R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-HOXD4/FITC Conjugated antibody
FITC标记的同源盒蛋白D4抗体
| 英文名称 | Anti-HOXD4/FITC |
| 中文名称 | FITC标记的同源盒蛋白D4抗体 |
| 别 名 | HHO.C13; homeo box D4; homeobox D4; Homeobox protein HHO.C13; Homeobox protein Hox-4B; Homeobox protein Hox-5.1; Homeobox protein Hox-D4; Hox-4.2; Hox-4.2, mouse, homolog of homeo box X; HOX-5.1; HOX4; HOX4B; HOXD4; HXD4_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 信号转导 结合蛋白 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Sheep, Spider Monkey |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 28kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human HOXD4 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that removed the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. The protein encoded by this gene may play a role in determining positional values in developing limb buds. Alternatively spliced variants have been described but their full length nature has not been determined. [provided by RefSeq, Jul 2008] Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Subcellular Location: Nucleus. Similarity: Belongs to the Antp homeobox family. Deformed subfamily. Contains 1 homeobox DNA-binding domain. Database links: Entrez Gene: 3233 Human Entrez Gene: 15436 Mouse Entrez Gene: 288153 Rat Omim: 142981 Human SwissProt: P09016 Human SwissProt: P10628 Mouse Unigene: 591609 Human Unigene: 430708 Mouse Unigene: 482194 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因属于同源异型盒基因家族。同源盒基因编码高度保守的转录因子家族，在所有多细胞生物的形态发生中起重要作用。哺乳动物具有四个相似的同源盒基因簇HOXA、HOXB、HOXC和HOXD，它们位于不同的染色体上，由9-11个基因串联排列。该基因是位于2q31-2q37染色体区域的几个同源盒HOXD基因之一。删除整个HOXD基因簇或该簇5’端的缺失与严重的肢体和生殖器异常有关。该基因编码的蛋白可能在确定肢体芽发育中的位置值方面起作用。替代剪接变异体已被描述，但它们的全长性质尚未确定。[ RefSeq，JUL 2008 ]